Enzyme advances promise to boost the bioeconomy

Enzyme advances promise to boost the bioeconomy

Enzyme advances promise to boost the bioeconomy

Enzyme technology symposium brings together researchers from North America and Japan working on cutting-edge applications.

By Stephanie Xenos

Around 85 researchers and industry partners involved in developing new enzyme-based applications recently came together at the University of Minnesota for the 1st North America-Japan Enzyme Technology Symposium. The symposium, organized by the BioTechnology Institute and Amano Enzyme Japan, focused on enzyme technology relating to biocatalysis and food, two key areas of the growing bioeconomy. 

“This symposium provided opportunities for new collaborations and learning about new enzyme applications that are particularly relevant for advancing the bioeconomy in Minnesota given the abundant agricultural and forest resources in our state,” says Claudia Schmidt-Dannert, director of the BioTechnology Institute.

Speakers covered a range of topics including modifications in the rate at which plants absorb light, in wood xylan to make polymers for food packaging, and in polyunsaturated fatty acids to make therapeutics.

“Enzyme applications make our lives better and our environment cleaner but most people are unaware of their importance since they work for us out of sight,” says Romas Kazlauskas, a professor in Biochemistry, Molecular Biology and Biophysics, and one of the organizers of the symposium. “Enzymes make our laundry detergents more effective, are used to make the COVID-19 drug Paxlovid, and improve the texture and taste of our foods. This symposium provided examples of current and future applications of enzymes.”

The symposium provided students and postdocs to engage with experts from industry and academia, and learn about the breadth of enzyme applications.

A selection of symposium talks are available to view.

BTI Faculty Members Dan Knights and Kechun Zhang Named 2015-2017 McKnight Land-Grant Professors

Please join us in congratulating Assistant Professors Dan Knights and Kechun Zhang, who were among the eight recipients of the 2015-2017 McKnight Land-Grant Professorship. The award is designed to advance the careers of promising junior faculty members who demonstrate the potential to make significant contributions to their departments and disciplines.

Dan Knights (BTI/Computer Science & Engineering)
Trillions of bacteria live in our guts, protecting us from infection and aiding our digestion. An imbalance of these bacteria, called dysbiosis, may contribute to obesity, diabetes, cancer, Crohn’s, and many other diseases, yet each person’s bacterial diversity is so distinct that we cannot easily identify when a microbiome is “unhealthy.” In his research, Dan combines expertise in data mining and biology to advance detection and treatment of dysbiosis in obesity and autoimmune diseases.

Kechun Zhang (BTI/Chemical Engineering & Materials Science)
Transforming traditional chemical production into a green and sustainable future is a great challenge facing human society. The current biorefinery process utilizes food resources and is limited by the metabolic capability of natural microorganisms. To enhance the viability of biomanufacturing, Kechun is engineering a new metabolic pathway in industrial yeast for more efficient fermentation of value-added chemicals from lignocellulosic feedstocks such as corn stover, sugar beet pulp, and citrus peel.

BTI’s Kechun Zhang recognized as an Early Innovator at the University of Minnesota’s Innovation awards.

Kechun Zhang (BTI, Chemical Engineering and Materials Science) was recognized on December 11th as an Early Innovator for his work developing a scalable, biodegradable, sugar-based rubber. A potential substitute for petroleum-based products, the biosynthetic rubber could appear in a variety of products, from grocery bags to bathtub toys. The Early Innovator award recognizes nontenured faculty or researchers who are actively engaged in developing new technologies and moving them to market.

Made in Minnesota: Celebrating University Innovators

The following BTI members were also recognized for patents and/or licenses awarded over the past three years: Alptekin Aksan, Wei-Shou Hu, Alexander Khoruts, Michael Sadowsky, Friedrich Srienc, Lawrence Wackett, Ping Wang and Kechun Zhang.

Mike Smanksi joins the BioTechnology Institute as assistant professor in the Department of Biochemistry, Molecular Biology, and Biophysics.

Mike Smanski joins the University of Minnesota from MIT, where he developed new strategies for engineering multi-gene systems as an HHMI Fellow of the Damon Runyon Cancer Research Foundation. Hired as part of the Synthetic Biology Cluster, Mike’s research focuses on natural product discovery and the precision engineering of bacterial species for biotechnological applications.  Read More

Linda Kinkel, Professor of Plant Pathology, joins BTI

Linda Kinkel, Professor of Plant Pathology, joins BTI

Linda Kinkel’s research focuses on the ecology of microbial communities in native prairie and agricultural soils. Kinkel’s work on the ecology and evolutionary biology of streptomycetes and other antibiotic producing bacteria has potential applications in the management of soil-borne plant pathogens.  Her current research, supported by MnDRIVE, will examine the impact of microbial inoculants and carbon inputs on disease suppression and plant productivity in Minnesota’s potato crop.  Learn more about Linda’s research.