Functional genomics, analysis of gene expression patterns, microarray applications; signal processing in relation to gene position on the chromosome. Mechanisms of adaptation in antibiotic-resistant bacteria and genomic landscape of starvation-recovery transitions in bacterial populations.
In his research, Arkady Khodursky focuses on mechanisms of adaptation in antibiotic resistant bacteria and the genomic landscape of starvation-recovery transitions in bacterial populations. His lab recently began investigating metabolic consequences of the acquired antibiotic resistance using topologically constrained metabolic modelling with the goal of identifying key modulators of the phenotypic variation. The lab also develops and tests experimental designs and statistical approaches to the basic analysis of transcriptomics data.