Wei-Shou Hu’s interests encompass cell engineering, tissue engineering and metabolic engineering. The emphasis of his research is on the application of systems analysis to biochemical and cellular systems and on the incorporation of physiological insight into the quantitative modeling of biological reactions. The systems employed in his work include mammalian cells, differentiated tissue cells and microorganisms. Current research efforts in the Hu lab emphasize employing genomic and proteomic tools in those research projects and exploring novel modeling approaches for quantitative description of cellular processes.