In his research, Mikael Elias seeks to decipher the mechanisms by which biological macromolecules evolve, to understand the molecular basis of their biological functions, and to develop new methods for their engineering. Long-term, Mikael is interested in developing soft, ecological solutions to current or emerging societal issues. The current methods used in the Elias Lab are spanning from molecular biology and microbiology, to protein engineering, structural biology and bioinformatics.